慢性運動性完全脊髄損傷後の地上歩行の回復

title
Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury.

author
Angeli CA, et al. N Engl J Med. 2018.

Abstract
Persons with motor complete spinal cord injury, signifying no voluntary movement or sphincter function below the level of injury but including retention of some sensation, do not recover independent walking. We tested intense locomotor treadmill training with weight support and simultaneous spinal cord epidural stimulation in four patients 2.5 to 3.3 years after traumatic spinal injury and after failure to improve with locomotor training alone. Two patients, one with damage to the mid-cervical region and one with damage to the high-thoracic region, achieved over-ground walking (not on a treadmill) after 278 sessions of epidural stimulation and gait training over a period of 85 weeks and 81 sessions over a period of 15 weeks, respectively, and all four achieved independent standing and trunk stability. One patient had a hip fracture during training. (Funded by the Leona M. and Harry B. Helmsley Charitable Trust and others; ClinicalTrials.gov number, NCT02339233 .).

memo
◼︎知らない
over-Ground Walking :地上歩行
Spinal Cord Injury :脊髄損傷
Complete :全部の、完全な
retention :保持、維持
epidural :硬膜外の
cervical :頚部の
gait :足ぶり、歩行
respectively :それぞれ、おのおの
fracture :骨折

◼︎使いたい
no voluntary movement or sphincter function below the level of injury
We tested intense locomotor treadmill training with weight support
one with damage to the mid-cervical region